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PRTA & BMS Collaboration

Updated: Aug 16, 2023

PRTA tech validated by big BMS collaboration

• BMS is part owner of PRTA

BMS & PRTA collaboration highlights:

3/20/18 CELG & PRTA enter master Collaboration agreement (CELG acquired by BMS - 2019)

• BMS may elect PRTA Abs against 3 targets

⇒ Tau, TDP-43, & undisclosed

⇒ $100M up-front

⇒ $50M for ~1.2M shares of PRTA

⇒ PRTA eligible for total of $2.2B fees & milestone

6/24/21 BMS $80M to PRTA for exclusive US rights to PRX005

7/5/23 BMS $55M to PRTA for exclusive WW rights to PRX005

⇒ BMS responsible for PRX005 going forward

⇒ Posible milestones now $562.5M

⇒ Reasonable royalty

PRX005 anti-tau Ab

• Binds microtubule binding region (MTBR)

⇒ R1, R2, and R3 repeats

⇒ tau 3R and 4R isoforms

⇒ Ph1 results @ #AAIC23 (healthy volunteers)

BMS to give PRX005 updates going forward

Article History:

Originally posted 7/17/23 (RB)

This is not investment, legal or tax advice. Do your own diligence and seek the advice of professionals.



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